| 纳米粒子探针及其在生物分析中的应用 |
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| 引用本文： | 谷峪,侯彩霞,韩利华,梁英华.纳米粒子探针及其在生物分析中的应用[J].材料工程,2010(8). |
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| 作者姓名： | 谷峪 侯彩霞 韩利华 梁英华 |
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| 作者单位： | 河北理工大学,化工与生物技术学院,河北,唐山,063000;河北理工大学,化工与生物技术学院,河北,唐山,063000;河北理工大学,化工与生物技术学院,河北,唐山,063000;河北理工大学,化工与生物技术学院,河北,唐山,063000 |
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| 摘 要： | 介绍了纳米粒子探针的概念、检测原理及分类。评述了纳米粒子探针在DNA检测、蛋白质检测及药物靶向运输中的应用,总结了纳米粒子探针在放大检测信号、避免蛋白质变质和有效降低负面效应等方面的优缺点,并对将来纳米粒子探针在有效靶向释药和多功能分析等方面的发展进行了展望。
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| 关 键 词： | 纳米粒子探针 生物分析 灵敏度 |
Nano-particle Probe and Application of Biological Analysis |
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| GU Yu,HOU Cai-xia,HAN Li-hua,LIANG Ying-hua.Nano-particle Probe and Application of Biological Analysis[J].Journal of Materials Engineering,2010(8). |
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| Authors: | GU Yu HOU Cai-xia HAN Li-hua LIANG Ying-hua |
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| Affiliation: | GU Yu,HOU Cai-xia,HAN Li-hua,LIANG Ying-hua (College of Chemical Engineering , Biotechnology,Hebei Polytechnic University,Tangshan 063000,Hebei,China) |
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| Abstract: | The definition,principle and classification of nano-particle probe were introduced.Furthermore,the use of DNA detection,protein analysis and deliver drugs were reviewed.The advantages and disadvantages of nano-particle probe were also summarized,such as amplify detection signal,avoid deterioration of protein and reduce the negative effects.And the developments of future nano-particle probe in the aspect of targeted drug delivery and multi-functional analysis were also discussed. |
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| Keywords: | nano-particle probe biological analysis sensitivity |
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