| 淀粉基口服结肠靶向给药控释载体 |
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| 引用本文： | 陈玲,黄嫣然,李晓玺.淀粉基口服结肠靶向给药控释载体[J].材料导报,2007,21(2):116-119. |
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| 作者姓名： | 陈玲 黄嫣然 李晓玺 |
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| 作者单位： | 华南理工大学轻化所,广州,510640;华南理工大学轻化所,广州,510640;华南理工大学轻化所,广州,510640 |
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| 基金项目： | 国家自然科学基金，广东省科技攻关计划，广东省广州市科技成果重点推广计划 |
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| 摘 要： | 通过合理改性来调控淀粉的消化性能,使其具有不被上消化道消化、但能够被结肠微生物酵解的特性,则可用作口服结肠靶向药物控释载体.综述了淀粉的结构、消化特性、影响淀粉消化特性的因素及其在口服结肠靶向药物控释载体中的应用前景.
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| 关 键 词： | 淀粉 抗消化淀粉 口服结肠靶向 药物载体 |
Starch-based Carrier for The Oral Colon-specific Drug Delivery System |
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| CHEN Ling,HUANG Yanran,LI Xiaoxi.Starch-based Carrier for The Oral Colon-specific Drug Delivery System[J].Materials Review,2007,21(2):116-119. |
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| Authors: | CHEN Ling HUANG Yanran LI Xiaoxi |
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| Affiliation: | Institute of Light and Chemical Engineering, South China University of Technology, Guangzhou 510640 |
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| Abstract: | Starch can not be digested in the upper gastrointestinal but can be microbially decomposed in colon by suitable modifications which control starch digestibility, thus it can be used as carrier for oral colon-specific drug delivery system. This article provides a review of starch structure, digestibility and its influencing factors and the application outlook of starch-based carrier for oral colon-specific drug delivery system. |
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| Keywords: | starch resistant starch oral colon-specific drug carrier |
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