In vitro corrosion resistance and cytotoxicity of novel TiNbTaZr alloy |
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| Authors: | Yong-yuan GUO Meng-qi CHENG De-sheng CHEN Xiao-bing XUE Xian-long ZHANG |
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| Affiliation: | 1. Orthopaedic Department, The Sixth Affiliated People''s Hospital, Medical School of Shanghai Jiao Tong University, Shanghai 200233, China;2. State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China |
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| Abstract: | A novel β type Ti35Nb2Ta3Zr alloy with low modulus (48 GPa) was fabricated using vacuum consumable arc melting. The corrosion resistance and cytotoxicity of Ti35Nb2Ta3Zr were evaluated. The open circuit potential, electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization methods were used to determine the corrosion resistance. In Ringer's solution, Ti35Nb2Ta3Zr alloy exhibits better corrosion resistance, as compared to that of Ti6Al4V and Ti. The cytotoxicity tests indicate that the biocompatibility of Ti35Nb2Ta3Zr is as good as Ti and Ti6Al4V which are widely used in biomedical fields. Based on corrosion resistance and cytotoxicity, the novel β type Ti35Nb2Ta3Zr alloy can be considered as a potential biomaterial. |
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