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| 二茂铁-肽衍生物的合成及对木瓜蛋白酶的检测 | |
| 引用本文： | 彭立新. 二茂铁-肽衍生物的合成及对木瓜蛋白酶的检测[J]. 化学世界, 2008, 49(7) |
| 作者姓名： | 彭立新 |
| 作者单位： | 湖南工学院化工系,湖南,衡阳,421008 |
| 摘 要： | 以二茂铁为起始原料合成了二茂铁-肽衍生物Boc-HN-Fca-Gly-Gly-Tyr-Arg-OMe,采用循环伏安法对Boc-HN-Fca-Gly-Gly-Tyr-Arg-OMe在乙醇溶液中的电化学性质进行了检测,并利用四肽H2N-Gly-Gly-Tyr-Arg-OMe可通过氢键与木瓜蛋白酶结合的性质,通过快速、灵敏、简单的生物电化学方法完成了其对木瓜蛋白酶的检测识别。 |
| 关 键 词： | Boc-NH-Fca-Gly-Gly-Tyr-Arg-OMe 合成 木瓜蛋白酶 检测 |
Synthesis of Boc-HN-Fca-Gly-Gly-Tyr-Arg-Ome and Detection of Bapain(PAP) |
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| PENG Li-xin. Synthesis of Boc-HN-Fca-Gly-Gly-Tyr-Arg-Ome and Detection of Bapain(PAP)[J]. Chemical World, 2008, 49(7) | |
| Authors: | PENG Li-xin |
| Abstract: | Boc-NH-Fca-Gly-Gly-Tyr-Arg-OMe was synthesized from serveral ferrocenoyl derivates.The method of CV(cyclic voltammetry) was carried out to observe the electrochemical properties of Boc-NH-Fca-Gly-Gly-Tyr-Arg-OMe.The detection of papain(PAP) making use of the action of Boc-NH-Fca-Gly-Gly-Tyr-Arg-OMe with protein by hydrogen bond was accomplished through fast,sensitive and simple electrochemical methods. |
| Keywords: | Boc-NH-Fca-Gly-Gly-Tyr-Arg-OMe synthesis papain(PAP) detection |
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