甜菊糖苷的安全性研究进展

本文全面介绍了甜菊糖苷及其代谢物甜菊醇在生化、毒理学方面的研究进展，认为除了质量规格资料尚显不足之外，大量动物实验未发现甜菊糖苷的急性、短期及遗传毒性，无致癌、促癌作用，对生长繁殖、胎鼠发育亦无明显影响，而且在南美、日本等地有长期的食用传统，是一种较为安全的天然甜味剂。

Study on the Stevioside''''s Safety

Stevioside is a safe natural sweetener with long edible history in South American and Japan This article introduces the latest developments on biochemical and toxicological studies of Stevioside and its metabolite steviol Although there was not enough information on specification available,many studies showed that stevioside has a very low acute oral toxicity No shout-term toxicity,genotoxicity and carcinogenity were found in these studies And Stevioside affected neither growth nor reproduction in hamsters