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Radiation demineralised bone enhanced osteoinductive capacity after transplantation
Authors:GO Phillips  S Al-Assaf  A du Plessis
Affiliation:a The Glyn O. Phillips Hydrocolloids Research Centre, North East Wales Institute, Mold Road, Wrexham LL11 2AW, North Wales, UK
b Phillips Hydrocolloid Research Ltd., 45 Old Bond Street, London W1S 4AQ, UK
c Centre for Water Soluble Polymers, North East Wales Institute, Mold Road, Wrexham LL11 2AW, North Wales, UK
d Gammatron (PTY) Ltd., P.O. Box 26378, Monument Part 0105, South Africa
e The School of Dentistry, Dankook University, Republic of Korea
Abstract:Using a mediating alkyne gas during the radiation treatment prevents the degradation of natural and synthetic polysaccharides and proteins. The product has higher viscosity and is more elastic than the original material and, therefore, gives enhanced functionality. Protein, within demineralised bone, too can be modified to give enhanced osteoinductive capacity after transplantation. Thus new functionalities can be achieved from the new products produced in food and medical products.
Keywords:Radiation  Polysaccharides  Cross-linking  Demineralised bone  Collagen  Molecular weight
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