| 邻苯二胺与苯甲醛合成苯并咪唑的研究 |
| |
| 引用本文： | 刘贤响,苏胜培,尹笃林,刘,姣.邻苯二胺与苯甲醛合成苯并咪唑的研究[J].化学与生物工程,2014(3):28-30. |
| |
| 作者姓名： | 刘贤响 苏胜培 尹笃林 刘 姣 |
| |
| 作者单位： | 石化新材料与资源精细利用国家地方联合工程实验室湖南师范大学化学化工学院,湖南长沙410081 |
| |
| 基金项目： | 湖南省教育厅科研资助项目（13C562）,湖南师范大学素年基金资助项目（21101） |
| |
| 摘 要： | 以邻苯二胺和苯甲醛为原料合成了苯并咪唑。考察了催化剂类型及用量、溶剂类型、反应温度、反应时间对目标产物苯并咪唑产率的影响。确定适宜的反应条件如下:邻苯二胺与苯甲醛物质的量比为2.5∶1、以偏钒酸铵为催化剂、m(偏钒酸铵)∶m(苯甲醛)为0.19∶1、以三氯甲烷为溶剂、反应温度为50℃、反应时间为4h,在此条件下,苯并咪唑产率高达81.3%。
|
| 关 键 词： | 苯并咪唑 邻苯二胺 苯甲醛 偏钒酸铵 催化 |
Synthesis of Benzimidazole with o-Phenylenediamine and Benzaldehyde |
| |
| LIU Xian-xiang,SU Sheng-pei,YIN Du-lin,LIU Jiao.Synthesis of Benzimidazole with o-Phenylenediamine and Benzaldehyde[J].Chemistry & Bioengineering,2014(3):28-30. |
| |
| Authors: | LIU Xian-xiang SU Sheng-pei YIN Du-lin LIU Jiao |
| |
| Affiliation: | 1.National ＆ Local Joint Engineering Laboratory for New Petro-Chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University ,Changsha 410081 ,China;) |
| |
| Abstract: | Benzimidazole was synthesized by the reaction of o-phenylenediamine and benzaldehyde.The effects of catalyst type and dosage,solvent type,reaction temperature and reaction time on the yield of the object product were investigated.When the reaction was carried out at 50 ℃ for 4 h with the molar ratio of o-phenylenediamine to benzaldehyde of 2.5 ∶ 1 and the mass ratio of catalyst ammonium metavanadate to benzaldehyde of 0.19：1,the yield of benzimidazole reached as high as 81.3％. |
| |
| Keywords: | benzimidazole o-phenylenediamine benzaldehyde ammonium metavanadate catalysis |
| 本文献已被 CNKI 维普 等数据库收录！ |
