| N-[(4-溴-3,5-二氟)苯基]马来酰亚胺合成 |
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| 引用本文： | 李延勋,姚新鼎,徐丽,雒廷亮,刘国际.N-[(4-溴-3,5-二氟)苯基]马来酰亚胺合成[J].精细化工,2011,28(1):97-100. |
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| 作者姓名： | 李延勋 姚新鼎 徐丽 雒廷亮 刘国际 |
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| 作者单位： | 郑州大学化工与能源学院,河南,郑州,450001 |
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| 摘 要： | 以马来酸酐和4-溴-3,5-二氟苯胺为原料,对甲苯磺酸为催化剂,甲苯/DMF为混合溶剂,采用溶剂共沸法,制备了N-(4-溴-3,5-二氟)苯基]马来酰亚胺,用FTIR、1HNMR和13CNMR对产物进行了结构表征,并对合成工艺进行优化,所得适宜工艺条件(以4-溴-3,5-二氟苯胺38.6 mmol计):催化剂对甲苯磺酸用量0.877 8 g,n(马来酸酐)/n(4-溴-3,5-二氟苯胺)=1.2,胺化反应时间为1.5 h,环化反应时间为2 h,产率可达92.6%。
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| 关 键 词： | N-[(4-溴-3 5-二氟)苯基]马来酰亚胺 马来酸酐 4-溴-3 5-二氟苯胺 耐热改性剂 精细化工中间体 |
Synthesis of N-[(4-Bromo-3,5-difluorine)-phenyl]Maleimide |
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| LI Yan-xun,YAO Xin-ding,XU Li,LUO Ting-liang,LIU Guo-ji.Synthesis of N-[(4-Bromo-3,5-difluorine)-phenyl]Maleimide[J].Fine Chemicals,2011,28(1):97-100. |
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| Authors: | LI Yan-xun YAO Xin-ding XU Li LUO Ting-liang LIU Guo-ji |
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| Affiliation: | LI Yan-xun,YAO Xin-ding,XU Li,LUO Ting-liang,LIU Guo-ji(School of Chemical and Energy Engineering,Zhengzhou University,Zhengzhou 450001,Henan,China) |
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| Abstract: | The N-(4-bromo-3,5-difluorine)-phenyl]maleimide was synthesized with maleic anhydride and 4-bromo-3,5-difluoroaniline via the solvent azeotropic method,using p-toluene sulfonic acid as the catalyst and toluene/DMF as the mixed solvent.The chemical structure of the product was confirmed by means of FTIR,1HNMR and 13HNMR methods.The synthesis process was optimized,and the suitable conditions were found as follows(based on 38.6 mmol 4-bromo-3,5-difluoroaniline),amount of p-toluene sulfonic acid 0.877 8 g,n(ma... |
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| Keywords: | N-[(4-bromo-3 5-difluorine)-phenyl]maleimide maleic anhydride 4-bromo-3 5-difluoroaniline heat resistant modifier fine chemical intermediates |
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