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Interaction between Ternary Rare Earth Complexes of Cinnamic Acid and Phenanthroline with DNA by Spectroscopy
作者姓名:郭东方  叶炎  曾正志
作者单位:College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000,China,College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000,China,College of Chemistry and Chemical Engineering,Lanzhou University,Lanzhou 730000,China
摘    要:Considerableattentionshavebeenpaidtothe salicylicacid,theendogenoussignalmoleculein plant,becauseofitsspecialbiologicalfunctionsin manybiologicalprocesses1].Someinvestigations havedemonstratedthatsalicylicacidcaneliminatethebiologicalfreeradicals,andprot…

关 键 词:无机化学  吸收光谱  稀土元素复合物  共振光散射

Interaction between Ternary Rare Earth Complexes of Cinnamic Acid and Phenanthroline with DNA by Spectroscopy
Guo Dongfang,Ye Yan,Zeng Zhengzhi.Interaction between Ternary Rare Earth Complexes of Cinnamic Acid and Phenanthroline with DNA by Spectroscopy[J].Journal of Rare Earths,2005,23(2):162-166.
Authors:Guo Dongfang  Ye Yan  Zeng Zhengzhi
Abstract:The interaction of ternary complexes RE(phen)(cin)3(H2O)](RE= Nd (III),Ce(III),Eu(III))with calf thymus DNA was investigated by electronic absorption spectroscopy, ethidium bromide(EB)-DNA quenching fluorescent spectra and resonance light scattering. All experimental results indicate that the three complexes bind to DNA by the electrostatic mode and the intercalative mode. It is predicted that these complexes show high anticancer activity or other biologic activity.
Keywords:inorganic chemistry  electrostatic and intercalative mode  EB-DNA quenching fluorescent spectroscopy  absorption spectroscopy  resonance light scattering  rare earth complexes
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