9H-xanthene-2,7-diols as antioxidants for autoxidation of linoleic acid |
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| Authors: | Tatsuo Yamamura Masaki Arashima Kazumi Nakatani Takafumi Ishida Fukiko Yamada Tomihiro Nishiyama |
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| Affiliation: | (1) Shiga Central Research Laboratories, Noevir Co., Ltd., 112-1 Okada-cho, Yokaichi, 527 Shiga, Japan;(2) Department of Applied Chemistry, Faculty of Engineering, Kansai University, 564 Osaka, Japan |
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| Abstract: | The antioxidant activities of 9H-xanthene-2,7-diols and α-tocopherol were studied during the oxidation of linoleic acid in a homogeneous solution and in an aqueous micelle dispersion. The antioxidant activities of 9H-xanthene-2,7-diols for both systems were 1.0–2.4 times greater relative to α-tocopherol. In addition, the 1,3,4,5,6,8-hexamethylxanthene-2,7-diol showed less cytotoxicity toward human fibroblasts than did 2,6-di-t-butyl-4-methylphenol. |
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| Keywords: | Antioxidant cytotoxicity linoleic acid α -tocopherol 9H-xanthene-2,7-diol |
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