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Fabrication and characterization of silk/forsterite composites for tissue engineering applications
Authors:Abbas Teimouri  Leila Ghorbanian  Alireza Najafi Chermahini  Rahmatollah Emadi
Affiliation:1. Department of Chemistry, Payame Noor University, P.O. Box 19395-4697, Tehran, Iran;2. Torabinejad Dental Research Center and Department of Oral and Maxillofacial Pathology, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran;3. Department of Chemistry, Isfahan University of Technology, Isfahan, 84154-3111, Iran;4. Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran
Abstract:In this research, novel composite scaffolds consisting of silk fibroin and forsterite powder were prepared by a freeze-drying method. In addition, the effects of forsterite powder contents on the structure of the scaffolds were investigated to provide an appropriate composite for bone tissue engineering applications. The morphology studies using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) techniques showed that the forsterite ceramic was well distributed throughout the structures of SF/forsterite scaffolds. Furthermore, the forsterite powder (up to 40 wt%) was homogenously distributed within the silk fibroin as a matrix.
Keywords:Ceramics  Forsterite  Microporous materials  Silk fibroin  Tissue engineering
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