| 纳米羟基磷灰石/聚酰胺66复合材料在模拟体液(SBF)中的表面生物活性研究 |
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| 引用本文： | 彭雪林,李玉宝,严永刚,张利,魏杰.纳米羟基磷灰石/聚酰胺66复合材料在模拟体液(SBF)中的表面生物活性研究[J].高技术通讯,2003,13(12):38-42. |
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| 作者姓名： | 彭雪林 李玉宝 严永刚 张利 魏杰 |
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| 作者单位： | 四川大学纳米生物材料研究中心,成都,610064 |
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| 基金项目： | 863计划 ( 2 0 0 2AADF3 2 0 1)，国家自然科学基金 ( 3 0 2 70 3 99)资助项目 |
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| 摘 要： | 通过纳米羟基磷灰石／聚酰胺66(n—HA／PA66)复合材料体外模拟体液(SBF)浸泡实验，以聚酰胺66(PA66)为对照，用IR、XRD、SEM和ICP等手段对材料的表面组成和形貌变化进行了分析，比较了PA66和n-HA／PA66复合材料的表面生物活性。结果表明，n-HA／PA66复合材料在SBF中其表面形成的HA沉积物为部分碳酸基团取代的磷灰石，而PA66在浸泡过程中Ca、P不在聚合物表面沉积；n-HA／PA66复合材料具有良好的生物活性，作为骨组织修复或替代材料具有较高的研究和应用价值。
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| 关 键 词： | 纳米羟基磷灰石／聚酰胺66复合材料 模拟体液 SBF 生物活性 骨组织材料 |
in Vitro Study on the Surface Bioactivity of Nano-Hydroxyapatite/Polyamide66 Composite |
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| Peng Xuelin,Li Yubao,Yan Yonggang,Zhang Li,Wei Jie.in Vitro Study on the Surface Bioactivity of Nano-Hydroxyapatite/Polyamide66 Composite[J].High Technology Letters,2003,13(12):38-42. |
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| Authors: | Peng Xuelin Li Yubao Yan Yonggang Zhang Li Wei Jie |
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| Abstract: | The surface bioactivity of PA66 and n-HA/PA66 by soaking in simulated body fluid(SBF) was studied. XRD, FTIR, SEM and ICP were employed to study the surface change and Ca, P concentration change in SBF. In SBF, it was found that HA precipitation and carbonate substituted HA took place at the surface of n-HA/PA66 composite.PA66,compared with n-HA/PA66 composite,had not such precipit ation on its surface. n-HA/PA66 composite has better bioactivity than PA66. n-HA/PA66 composite may be used as bone-repaire and bone-substitute materials in the future. |
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| Keywords: | Simulated body fluid Nano-hydroxyapatite Polyamide66 Composite Bioactivity |
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