Multiblock copolymers based on segments of poly (D,L‐lactic‐glycolic acid) and poly(ethylene glycol) or poly(ϵ‐caprolactone): A comparison of their thermal properties and degradation behavior期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Multiblock copolymers based on segments of poly (D,L‐lactic‐glycolic acid) and poly(ethylene glycol) or poly(ϵ‐caprolactone): A comparison of their thermal properties and degradation behavior

Authors:	Maurizio Penco Fabio Bignotti Luciana Sartore Salvatore D'Antone Alberto D'Amore

Abstract:	A comparison of the thermal properties of two classes of poly(D,L ‐lactic‐glycolic acid) multiblock copolymers is reported. In particular, the results of differential scanning calorimetry, and thermogravimetric analysis of copolymers containing poly(ethylene glycol) (PEG) or diol‐terminated poly(ϵ‐caprolactone) (PCDT) segments are described. The influence of the chemical structure and the length of PEG and PCDT on thermal stability, degree of crystallinity and glass transition temperature (T_g ) is discussed. Finally, an evaluation of the hydrolytic behavior in conditions mimicking the physiological environment is reported. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 78: 1721–1728, 2000

Keywords:	poly(lactic‐glycolic acid) poly(D,L‐lactic‐glycolic acid) diol‐terminated poly(ϵ ‐caprolactone) poly(ethylene glycol) block copolymers bioerodible polymers thermal properties thermal degradation, hydrolytic degradation