| 高温烧结羟基磷灰石靶的细胞相容性 |
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| 引用本文： | 罗乐,赵读亮,蒋大鹏,严中亚,程光存,方晓东.高温烧结羟基磷灰石靶的细胞相容性[J].量子电子学报,2014,31(3):368-371. |
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| 作者姓名： | 罗乐 赵读亮 蒋大鹏 严中亚 程光存 方晓东 |
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| 作者单位： | 1 合肥工业大学电子科学与应用物理学院；安徽合肥；230009， China；2 安徽省立医院胸心外科；安徽 合肥，230001；3 中国科学院安徽光学精密机械研究所，安徽 合肥，230031 |
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| 摘 要： | 为研究高温烧结羟基磷灰石靶的细胞相容性，把纯度为99%的羟基磷灰石粉末压制成圆盘形靶，在氩气中在800℃高温下烧结成型。用X射线衍射仪和X射线光电子能谱仪对羟基磷灰石靶的结构组成进行检测。用四氮唑盐比色法对羟基磷灰石靶的细胞相容性进行检测。检测结果表明：纯度为99%的羟基磷灰石粉末在压制成型和800℃高温烧结的过程中化学组成没有发生变化，羟基磷灰石靶中的平均粒径为78.2nm、结晶度为89.4%、Ca/P比值为1.592，具有很好的细胞相容性。
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| 关 键 词： | 材料 羟基磷灰石靶 高温烧结 钙磷比 细胞相容性 |
Cellular Compatibility of Hydroxyapatite Target Sintered at High Temperature |
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| LUO Le,ZHAO Duliang,JIANG Dapeng,YAN Zhongya,CHENG Guangcun,FANG Xiaodong.Cellular Compatibility of Hydroxyapatite Target Sintered at High Temperature[J].Chinese Journal of Quantum Electronics,2014,31(3):368-371. |
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| Authors: | LUO Le ZHAO Duliang JIANG Dapeng YAN Zhongya CHENG Guangcun FANG Xiaodong |
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| Affiliation: | 1, Electronics and Applied Physics School, Hefei University of Technology, Hefei City Anhui Province 230009)
(2, Department of Cardiac Surgery, Anhui Provincial Hospital, Hefei City Anhui Province 230001)
(3, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Science, Hefei City Anhui Province 230031) |
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| Abstract: | In order to study cellular compatibility of hydroxyapatite(HA) target sintered at high temperature, the powder of 99% pure hydroxyapatite was pressed to discal targets and the targets were sintered at 800℃ in argon ambience. The microstructure and composition of targets were detected with X-ray diffractometer(XRD) and the X-ray photoelectron spectroscopy(XPS). The cellular compatibility of targets was detected with Methyl Thiazolyl Tetrazolium(MTT). The experimental result demonstrates the chemical composition of targets was not changed while the powder of hydroxyapatite was pressed to targets and the targets were sintered at 800℃ in argon ambience. The average particle diameter in target was 78.2nm, the crystallinity in target was 89.4% and the ratio of Ca to P in target was 1.592. The hydroxyapatite target sintered at 800℃ had cellular compatibility. |
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| Keywords: | materials hydroxyapatite target sintering at high temperature ratio of Ca to P cellular compatibility |
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