Composition and Structure of Fibrous Hydroxyapatite Growth on an Injectale Bone Tissue Engineering Scaffolds Material

1Introduction Thetreatmentofbonedefectsinducedbyinjuryor pathologicalchangecouldbenefitfrombiocompatiblema terialsbasedonbiodegradablepolymerthatassistinthe boneregeneration.Thesepolymersareverypromisingasa temporarystabilizationforaugmentationoffracturef…

Composition and Structure of Fibrous Hydroxyapatite Growth on an Injectale Bone Tissue Engineering Scaffolds Material

Fibrous hydroxyapatite(HA) was grown upwards from the crosslinked unsaturated polyphosphoester(UPPE) which was used as an injectable bone tissue engineering scaffolds. Composition of fibrous HA was determined by FT-IR, XRD and EDX, which suggested that the fibrous HA was calcium deficient carbonated apatite with low crystallinity. SEM micrographs indicated that the fibrous HA had a hollow tubing structure and tube wall was a flakelike assembly. The fibre with poor mechanical property and with a growth rate about 0.5 mm/min reached several centimeters in length after 2 hours. The growth was at the tip of the fibre suggested that the procedure of forming fibrous HA was as follows: Ca 2 ions were firstly incorporated into the crosslinked UPPE by dipping in Ca 2 solution, then supplied through micropores of the material reacted with PO 3-_4 ions to form a small tube, the osmotic pressure or capillary force lead the Ca 2 continuously gushed out into the PO 3-_4 solution, thus fibrous HA was obtained.