| N-乙酰-L-半胱氨酸修饰的CdTe量子点与人血清白蛋白的相互作用 |
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| 引用本文： | 张龙,胡新根,方国勇. N-乙酰-L-半胱氨酸修饰的CdTe量子点与人血清白蛋白的相互作用[J]. 广东化工, 2011, 0(8): 23-24,22 |
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| 作者姓名： | 张龙 胡新根 方国勇 |
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| 作者单位： | 温州大学化学与材料工程学院; |
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| 摘 要： | 以N，乙酰-L-半胱氨酸为修饰剂，制备了水溶性的CdTe量子点（NAc—CdTeQDs）。利用荧光光谱法和等温滴定量热法（11℃）研究了NAC-CdTeQDs与人血清白蛋白（HsA）的相互作用。结果表明，NAC—CdTeQDs对HSA内源荧光具有较强的动态猝灭作用，且猝灭作用是扩散控制的。
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| 关 键 词： | N-乙酰-L-半胱氧酸：碲化镉：量子点 人血清白蛋白 荧光猝灭 等温滴定量热 |
Interaction of N-Acetyl-L-Cysteine Capped CdTe Quantum Dots with Human Serum Albumin |
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| Zhang Long,Hu Xingen,Fang Guoyong. Interaction of N-Acetyl-L-Cysteine Capped CdTe Quantum Dots with Human Serum Albumin[J]. Guangdong Chemical Industry, 2011, 0(8): 23-24,22 |
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| Authors: | Zhang Long Hu Xingen Fang Guoyong |
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| Affiliation: | Zhang Long,Hu Xingen,Fang Guoyong(College of Chemistry and Material Engineering,Wenzhou University,Wenzhou 325035,China) |
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| Abstract: | Using N-acetyl-L-cysteine(NAC) as stabilizer,water-soluble CdTe quantum dots(NAC-CdTe QDs) were prepared.The interaction between NAC-CdTe QDs and human serum albumin(HSA) was investigated by fluorescence spectroscopy and isothermal titration calorimetry(ITC).The fluorescence measurement result showed that intrinsic fluorescence of HSA was strongly quenched by NAC-CdTe QDs in the range of certain concentration,and the quenching mechanism of HSA by NAC-CdTe QDs was considered to be a dynamic quenching which w... |
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| Keywords: | N-acetyl-L-cysteine CdTe quantum dots human serum albumin fluorescence quenching isothermal titration calorimetry |
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