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A biotechnological perspective on the application of iron oxide nanoparticles
Authors:Farnaz Assa  Hoda Jafarizadeh-Malmiri  Hossein Ajamein  Navideh Anarjan  Hamideh Vaghari  Zahra Sayyar  Aydin Berenjian
Affiliation:1. Faculty of Chemical Engineering, Sahand University of Technology, Tabriz 5331811111,Iran;2. Department of Chemical Engineering, Ilkhchi Branch, Islamic Azad University, Ilkhchi 5358114418,Iran;3. Department of Chemical Engineering, Tabriz Branch, Islamic Azad University, Tabriz 5157944533,Iran;4. School of Engineering, Faculty of Science and Engineering, University of Waikato, Hamilton 3240, New Zealand
Abstract:In recent decades,magnetic iron nanoparticles (NPs) have attracted much attention due to properties such as superparamagnetism,high surface area,large surface-to-volume ratio,and easy separation under external magnetic fields.Therefore,magnetic iron oxides have potential for use in numerous applications,including magnetic resonance imaging contrast enhancement,tissue repair,immunoassay,detoxification of biological fluids,drug delivery,hyperthermia,and cell separation.This review provides an updated and integrated focus on the fabrication and characterization of suitable magnetic iron NPs for biotechnological applications.The possible perspective and some challenges in the further development of these NPs are also discussed.
Keywords:iron oxide nanoparticle  superparamagnetic  biotechnology  surface modification
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