A biotechnological perspective on the application of iron oxide nanoparticles |
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Authors: | Farnaz Assa Hoda Jafarizadeh-Malmiri Hossein Ajamein Navideh Anarjan Hamideh Vaghari Zahra Sayyar Aydin Berenjian |
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Affiliation: | 1. Faculty of Chemical Engineering, Sahand University of Technology, Tabriz 5331811111,Iran;2. Department of Chemical Engineering, Ilkhchi Branch, Islamic Azad University, Ilkhchi 5358114418,Iran;3. Department of Chemical Engineering, Tabriz Branch, Islamic Azad University, Tabriz 5157944533,Iran;4. School of Engineering, Faculty of Science and Engineering, University of Waikato, Hamilton 3240, New Zealand |
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Abstract: | In recent decades,magnetic iron nanoparticles (NPs) have attracted much attention due to properties such as superparamagnetism,high surface area,large surface-to-volume ratio,and easy separation under external magnetic fields.Therefore,magnetic iron oxides have potential for use in numerous applications,including magnetic resonance imaging contrast enhancement,tissue repair,immunoassay,detoxification of biological fluids,drug delivery,hyperthermia,and cell separation.This review provides an updated and integrated focus on the fabrication and characterization of suitable magnetic iron NPs for biotechnological applications.The possible perspective and some challenges in the further development of these NPs are also discussed. |
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Keywords: | iron oxide nanoparticle superparamagnetic biotechnology surface modification |
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