| 对甲基苯甲醚相转移催化合成工艺探讨 |
| |
| 引用本文： | 高中锋,侯广强,范若静,高晓宇,徐建国,孙学军. 对甲基苯甲醚相转移催化合成工艺探讨[J]. 当代化工, 2010, 39(3): 259-260,264 |
| |
| 作者姓名： | 高中锋 侯广强 范若静 高晓宇 徐建国 孙学军 |
| |
| 作者单位： | 曲阜师范大学化学与化工学院山东省生命有机分析重点实验室,山东,曲阜,273165;曲阜弘利化工有限公司,山东,曲阜,273165 |
| |
| 摘 要： | 以四丁基溴化铵为相转移催化剂,催化对甲苯酚与硫酸二甲酯反应合成对甲基苯甲醚,并对催化剂的用量、反应物料比、反应时间、反应温度等因素对产物收率的影响进行了讨论。结果表明,在硫酸二甲酯和对甲苯酚的摩尔比为1.4,相转移催化剂质量分数为6%,pH=8,水浴控温50～60℃,反应时间为6 h条件下,对甲基苯甲醚的产率最高可达92.36%。
|
| 关 键 词： | 有机合成 工艺研究 相转移催化 对甲基苯甲醚 |
Phase Transfer Catalyzed Synthesis of p-methyl Anisole |
| |
| GAO Zhong-feng,HOU Guang-qiang,FAN Ruo-jing,GAO Xiao-yu,XU Jan-guo,SUN Xue-jun. Phase Transfer Catalyzed Synthesis of p-methyl Anisole[J]. Contemporary Chemical Industry, 2010, 39(3): 259-260,264 |
| |
| Authors: | GAO Zhong-feng HOU Guang-qiang FAN Ruo-jing GAO Xiao-yu XU Jan-guo SUN Xue-jun |
| |
| Affiliation: | 1.Key Laboratory of Life-Organic Analysis of Shandong Province,College of Chemistry Science,Qufu Normal University,Shandong Qufu 273165,China;2.Qufu Hongli Chemical Co.Ltd,Shandong Qufu 273165,China) |
| |
| Abstract: | Using tetrabutyl ammonium bromide as phase transfer catalyst,p-methyl anisole was synthesized from p-cresol and dimethyl sulfate.Effects of catalyst dosage,reaction material ratio,reaction time,reaction temperature and other factors on the yield of the product were discussed.The results show that when molar ratio of dimethyl sul-fate and p-cresol is 1.4,the phase transfer catalyst dosage is 6%,pH = 8,water bath temperature is at 50～60 ℃,re-action time is 6 h,the yield of p-methyl anisole can be up to 92.36%. |
| |
| Keywords: | Organic Synthesis Technology Phase Transfer Catalysis p-methyl anisole |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
