Zur Synthese von Octahydrochinazolinonen und deren Reaktion mit Persäure

The Synthesis of Octahydroquinazolinones and their Reaction with Peracid By reaction of cyclohexanone-2-carboxamide with ammonia and aldehydes, octahydroquinazolinones 2a–f , and with Schiff bases octahydroquinazolinones 3a–c are formed. 2-Hydroxycyclohexanone-2-carboxamide forms with ammonia and butyraldehyde the hydroxyocta-hydroquinazolinone 4 . Compound 2e reacts with monoperoxiphthalic acid to the hydroxyoxaziridine 5e which reacts with alkali hydroxide to compound 6. 8 yields with peroxy acid the hydroperoxy epoxide 9 .