虎尾草黄酮类化学成分研究

对虎尾草药材地上部分用70%乙醇提取后,以大孔吸附树脂、聚酰胺和硅胶等分离材料进行分离和纯化,从中分得10个黄酮类化合物,利用氢谱、碳谱、质谱和颜色反应等手段对其结构进行确认,10个化合物依次为槲皮素(Ⅰ)、山奈酚(Ⅱ)、异鼠李素(Ⅲ)、槲皮素-3-O-β-葡萄糖苷(异槲皮苷)(Ⅳ)、槲皮素-3-O-α-L-鼠李糖苷(槲皮苷)(Ⅴ)、山奈酚-3-O-β-D-葡萄糖苷(Ⅵ)、山奈酚-3-O-β-D-半乳糖苷(Ⅶ)、金丝桃苷(Ⅷ)、异鼠李素-3-O-β-D-芸香糖苷(Ⅸ)和芦丁(Ⅹ),其中化合物Ⅴ、Ⅵ为首次从该植物中分离得到,化合物Ⅲ、Ⅸ为首次从该属植物中分离得到。

Chemical Constituents of Flavonoids from Lysimachia Barystachys Bunge

Ten compounds were extracted by 70%ethanol and then isolated with silica gel and polyamide chromatography from the aerial parts of Lysimachia barystachys Bunge.Their structures were determined by spectral analysis and chemical evidence.They were identified as quercetin(Ⅰ),kaempferol(Ⅱ),isorhamnetin(Ⅲ),quercetin-3-O-β-D-glucoside(Ⅳ),quercitrin(Ⅴ),kaempferol-3-O-β-D-glucoside (Ⅵ),kaempferol-3-O-β-D-galactoside(Ⅶ),hyperoside(Ⅷ),isorhamnetin-3-O-β-D-rutinoside(Ⅸ)and rutin (Ⅹ).Compounds Ⅴ,Ⅵ were isolated from this plant and compounds Ⅲ,Ⅸ were isolated from this genus for the first time.