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Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice
Authors:S Joseph  J David  T Joseph
Affiliation:Howard Hughes Medical Institute, University of California at San Diego, La Jolla 92093-0649, USA. kristin@flyeye.ucsd.edu
Abstract:Calcium influx through the TRP and TRPL light-activated channels triggers a complex regulatory hierarchy resulting in positive and negative feedback regulation of the phototransduction cascade. Recent studies have begun to elucidate the function of TRP and TRPL in vivo, and to examine their relationship to intracellular calcium changes during the light response.
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