| ????ESI-Q-TOF-MS/MS???????????Rh2??CK |
| |
| 引用本文： | 孙靖辉,吴巍,郭迎迎,秦秋杰,刘淑莹.????ESI-Q-TOF-MS/MS???????????Rh2??CK[J].质谱学报,2014,35(2):158-162. |
| |
| 作者姓名： | 孙靖辉 吴巍 郭迎迎 秦秋杰 刘淑莹 |
| |
| 作者单位： | 1.????????????????????ο???о???????? ????130117??2.???????????????? ????132013??3.?й???????????????о?????????????????????? ????130022 |
| |
| 基金项目： | 吉林省科技发展重大项目(20096043);吉林省高校创新团队发展计划项目(JTD201213)资助 |
| |
| 摘 要： | ?????????????????????????????????Rh2??CK????????????????????-?????-?????????????(ESI-Q-TOF-MS/MS)???????????????????????????2??ò???????????????????????????Rh2??CK????MS/MS?о??????????????????????￡????????????????????????????????????????????￡?Rh2???????????????????????CK????????????????????????￡??????????????????????CK??????????20??40??60 eV??????????????????m/z 465??m/z 203????Rh2??????????????60 eV???????????????????????????Rh2??CK??MS/MS??????????????????????????????塣
|
| 关 键 词： | ??????-?????-?????????????(ESI-Q-TOF-MS/MS) ??????? ??????? |
Differentiation of Ginsenoside Isomers Rh2 and CK Using ESI-Q-TOF-MS/MS |
| |
| SUN Jing-hui,WU Wei,GUO Ying-ying,QIN Qiu-jie,LIU Shu-ying.Differentiation of Ginsenoside Isomers Rh2 and CK Using ESI-Q-TOF-MS/MS[J].Journal of Chinese Mass Spectrometry Society,2014,35(2):158-162. |
| |
| Authors: | SUN Jing-hui WU Wei GUO Ying-ying QIN Qiu-jie LIU Shu-ying |
| |
| Affiliation: | 1. Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China; 2. Pharmaceutical College, Beihua University, Jilin 132013, China; 3. Changchun Center of Mass Spectrometry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China |
| |
| Abstract: | A rapid analysis method of electrospray-quadrupole-time-of-flight mass spectrometry (ESI-Q-TOF-MS/MS) was established to differentiate ginsenoside isomers Rh2 and compound K (CK). Based on the analysis of MS/MS product ions with different collision energy in both negative and positive ion mode, ginsenoside isomers Rh2 and CK are distinguished. The results show that the fragmentation pathway of Rh2 and CK in negative ion mode is similar. The difference is that the fragment ion abundance of Rh2 is significantly lower than that of CK with the same collision energy. The fragmentation behavior of Rh2 is different from CK in positive ion mode, specific fragment ions m/z 465 and m/z 203 are produced with collision energy 20, 40 and 60 eV in CK, but Rh2 produces the similar specific fragment ions only with collision energy 60 eV in MS/MS. The MS/MS fragmentation pathway is particularly useful in the identification of ginsenoside isomers Rh2 and CK. |
| |
| Keywords: | electrospray-quadrupole-time-of-flight mass spectrometry (ESI-Q-TOF-MS/MS） ginsenoside isomer |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《质谱学报》浏览原始摘要信息 |
|
点击此处可从《质谱学报》下载全文 |
