木糖与木糖醇色谱分离操作的质量优化

利用模拟移动床（SMB）连续色谱技术分离木糖醇母液中的木糖和木糖醇组分。在平衡理论的框架下,提出了使用基于相应的真实移动床（TMB）的简化数学模型,来研究各进料液和产品流出液的流量等操作参数的变化,对SMB分离性能（以纯度和收率作为性能指标）影响的方法。采用本方法进行了操作条件寻优仿真,并取得满意结果。在实验室SMB分离设备上,基于此最佳操作条件所得到的木糖和木糖醇产品液纯度和收率均达到100％。

Optimization of Chromatographic Separation Operation for Xylose and Xylitol

Abstract: The simulated moving bed (SMB) chromatographic technique has been used to separate the xylitol mother liquor into xylitol component. In the frame of equilibrium theory , characterized by purity and recovery, a new method is presented to study the influences of inlet and outlet flow - rate upon the 8MB performance by using a simplified mathematical model of the corresponding true moving bed (1MB) . Then, the operation condi-tions are optimized by computer simulation with the method and the satisfaction result is got . By using a 8MB equipment of our lab , 100% purities and recoveries in the xylose and xylitol product liquor are obtained ac-cording to the optimized operation conditions.