| 光动力疗法对巨噬细胞作用研究进展 |
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| 引用本文： | 张文涛,杨伟江,罗杰夫,杨涛,陈劲弈,谭杨,雷霞. 光动力疗法对巨噬细胞作用研究进展[J]. 激光杂志, 2020, 41(2): 1-4. DOI: 10.14016/j.cnki.jgzz.2020.02.001 |
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| 作者姓名： | 张文涛 杨伟江 罗杰夫 杨涛 陈劲弈 谭杨 雷霞 |
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| 作者单位： | 陆军军医大学大坪医院,重庆400042;陆军军医大学大坪医院,重庆400042;陆军军医大学大坪医院,重庆400042;陆军军医大学大坪医院,重庆400042;陆军军医大学大坪医院,重庆400042;陆军军医大学大坪医院,重庆400042;陆军军医大学大坪医院,重庆400042 |
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| 摘 要： | 光动力疗法(Photodynamic Therapy,PDT)是指利用光敏剂在病变组织内聚集,在特定的波长的光或者激光的照射下被激活,产生单态氧或者其他自由基,造成病变组织坏死,不损伤正常组织的疗法[1]。这些年来,PDT已经得到了广泛的应用,越来越多的研究者开始关注着它的机制。近年来许多研究发现PDT对巨噬细胞吞噬活性及其极化具有重大作用。本文就拟对PDT对巨噬细胞的作用及机制进行阐述。
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| 关 键 词： | 光动力疗法(PDT) 巨噬细胞 极化 吞噬活性 |
Research progress on the effect of photo-dynamic therapy on macro-phages |
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| ZHANG Wentao,YANG Weijiang,LUO Jiefu,YANG Tao,CHEN Jinyi,TAN Yang,LEI Xia. Research progress on the effect of photo-dynamic therapy on macro-phages[J]. Laser Journal, 2020, 41(2): 1-4. DOI: 10.14016/j.cnki.jgzz.2020.02.001 |
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| Authors: | ZHANG Wentao YANG Weijiang LUO Jiefu YANG Tao CHEN Jinyi TAN Yang LEI Xia |
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| Affiliation: | (Department of Dermatology,Daping Hospital,Army Medical University,Chongqing 400042,China) |
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| Abstract: | Photo-dynamic therapy(PDT)refers to the therapy using photo-sensitizers to accumulate in the diseased tissue and can be activated under specific wavelength of light or laser irradiation to generate singlet oxygen or other free radicals,resulting in necrosis of the diseased tissue without damaging the normal tissue".Over the years,PDT has been widely used,more and more researchers began to pay attention to its mechanism.In recent years,It has found that PDT plays an important role in phagocytic activity and polarization of macro-phages in many studies.This paper intends to expound the effect and mechanism of PDT on macro-phages. |
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| Keywords: | photo-dynamic therapy(PDT) macrophage polarization phagocytosis activity |
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