Preparation and analysis of chemically gradient functional bioceramic coating formed by pulsed laser deposition |
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Authors: | P Rajesh C V Muraleedharan S Sureshbabu Manoj Komath Harikrishna Varma |
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Affiliation: | (1) Bioceramics Laboratory, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, 695012, Kerala, India;(2) Division of Artificial Internal Organs, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, 695012, Kerala, India; |
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Abstract: | Bioactive ceramic coatings based on calcium phosphates yield better functionality in the human body for a variety of metallic
implant devices including orthopaedic and dental prostheses. In the present study chemically and hence functionally gradient
bioceramic coating was obtained by pulsed laser deposition method. Calcium phosphate bioactive ceramic coatings based on hydroxyapatite
(HA) and tricalcium phosphate (TCP) were deposited over titanium substrate to produce gradation in physico-chemical characteristics
and in vitro dissolution behaviour. Sintered targets of HA and α-TCP were deposited in a multi target laser deposition system.
The obtained deposits were characterized by X-ray diffraction, fourier transform infrared spectroscopy, scanning electron
microscopy and energy dispersive X-ray analysis. Inductively coupled plasma spectroscopy was used to estimate the in vitro
dissolution behaviour of coatings. The variation in mechanical property of the gradient layer was evaluated through scratch
test and micro-indentation hardness. The bioactivity was examined in vitro with respect to the ability of HA layer to form
on the surface as a result of contact with simulated body fluid. It could be inferred that chemically gradient functional
bioceramic coating can be produced by laser deposition of multiple sintered targets with variable chemical composition. |
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