| 一种含三嗪环的四臂引发核的合成与表征 |
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| 引用本文： | 林休休,刘小红,徐冬梅,张可达.一种含三嗪环的四臂引发核的合成与表征[J].精细化工,2007,24(2):194-198. |
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| 作者姓名： | 林休休 刘小红 徐冬梅 张可达 |
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| 作者单位： | 苏州大学,化学化工学院,江苏省有机合成重点实验室,江苏,苏州,215123 |
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| 基金项目： | 江苏省教育厅自然科学基金
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苏州大学在职获得博士学位人员科研资助经费
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苏州大学校科研和教改项目 |
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| 摘 要： | 以三聚氯氰(CNC)和乙二胺(EDA)为原料,通过亲核取代反应合成了含1,3,5-三嗪环的四臂引发核:N,N′-二-(4,6-二氯-1,3,5]-三嗪基)-乙二胺。考察了反应物投料摩尔比,碱的种类和用量,加料速率和反应时间对产物收率的影响。结果表明:n(CNC)∶n(EDA)=2∶1,碱用NaOH,且n(NaOH)∶n(EDA)=2∶1,以V(二氯甲烷)∶V(水)=1∶1为溶剂,乙二胺的NaOH水溶液的滴加速率为1 mL/m in,0~5℃反应2 h,收率达95.5%。通过元素分析、质谱、核磁共振、红外光谱对目标产物的结构进行了分析表征。
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| 关 键 词： | 四臂引发核 N N′-二-(4 6-二氯-[1 3 5]-三嗪基)-乙二胺 三聚氯氰 乙二胺 |
| 文章编号： | 1003-5214（2007）02-0194-05 |
| 修稿时间： | 2006-07-032006-09-19 |
Synthesis and Characterization of a Four-arm Initiating Core Containing 1,3,5-Triazine |
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| LIN Xiu-xiu,LIU Xiao-hong,XU Dong-mei,ZHANG Ke-da.Synthesis and Characterization of a Four-arm Initiating Core Containing 1,3,5-Triazine[J].Fine Chemicals,2007,24(2):194-198. |
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| Authors: | LIN Xiu-xiu LIU Xiao-hong XU Dong-mei ZHANG Ke-da |
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| Affiliation: | Key Laboratory of Organic Synthesis of Jiangsu Province, Institute of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215123, Jiangsu , China |
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| Abstract: | A Four-arm initiating core containing 1,3,5-triazine,N,N′-bis-(4,6-dichloro——triazin-2-yl)-ethane-1,2-diamine,was prepared from cyanuric chloride(CNC) and ethylene diamine(EDA) by nucleophilic substitution reaction.The optimum reaction conditions included n(CNC)∶n(EDA)=2∶1,NaOH used as base,n(NaOH)∶n(EDA)=2∶1,dichloromethane and water in volume ratio 1∶1 as solvent,adding rate of aqueous NaOH solution of EDA 1 mL/min,reaction temperature 0～5 ℃ and reaction time 2 h.The product yield reached 95.5%.Structure of the target product was characterized by elementary analysis,MS,~1 HNMR and FTIR. |
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| Keywords: | four-arm initiating core N N′-bis-(4 6-dichloro-triazin-2-yl)-ethane-1 2-diamine cyanuric chloride ethylene diamine |
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