Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears |
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Authors: | Laura Cussonneau,Cé cile Coudy-Gandilhon,Christiane Deval,Ghita Chaouki,Mehdi Djelloul-Mazouz,Yoann Delorme,Julien Hermet,Guillemette Gauquelin-Koch,Cé cile Polge,Daniel Taillandier,Julien Averous,Alain Bruhat,Cé line Jousse,Isabelle Papet,Fabrice Bertile,Etienne Lefai,Pierre Fafournoux,Anne-Catherine Maurin,Lydie Combaret |
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Affiliation: | 1.Université Clermont Auvergne, INRAE, UNH UMR 1019, CRNH Auvergne, 63000 Clermont-Ferrand, France;2.Centre National d’Etudes Spatiales, CNES, 75001 Paris, France;3.Université de Strasbourg, CNRS, IPHC UMR 7178, 67037 Strasbourg, France |
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Abstract: | |
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Keywords: | skeletal muscle, unloading, hindlimb suspension, halofuginone, ATF4, TGF-β /BMP signalling, hibernating bear, atrogenes, muscle atrophy |
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