| 头孢克肟干混悬剂的有关物质研究 |
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| 引用本文： | 武玉洁,常明,高岩磊,张雪红. 头孢克肟干混悬剂的有关物质研究[J]. 河北化工, 2011, 34(7): 4-5,8 |
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| 作者姓名： | 武玉洁 常明 高岩磊 张雪红 |
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| 作者单位： | 1. 河北九派制药有限公司,河北石家庄,050011
2. 石家庄学院化工学院,河北石家庄,050035 |
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| 摘 要： | 建立了头孢克肟有关物质的检测方法。采用高效液相色谱法,色谱柱为C18柱,流动相为四丁基氢氧化铵乙腈（75∶25）,检测波长为254 nm,柱温为40℃,进行检测头孢克肟的检测限为2 ng。该法可靠、专属、快速,可作为头孢克肟有关物质的检测方法。
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| 关 键 词： | 头孢克肟 干混悬剂 HPLC 有关物质 |
Determination of Ibuprofen and Its Related Substances in Injection by HPLC |
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| WU Yu-jie,CHANG Ming,GAO Yan-lei,ZHANG Xue-hong. Determination of Ibuprofen and Its Related Substances in Injection by HPLC[J]. Hebei Chemical Engineering and Industry, 2011, 34(7): 4-5,8 |
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| Authors: | WU Yu-jie CHANG Ming GAO Yan-lei ZHANG Xue-hong |
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| Affiliation: | 1.Hebei Jiupai Pharmacetuical Co.,Ltd,Shijiazhuang 050011,China;2.College of Chemical Engineering,Shijiazhuang University,Shijiazhuang 050035,China) |
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| Abstract: | To establish an HPLC method for the determination of the related substances of cefixime in suspension.The se-paration was performed on C18 column.The mobile phase was composed of tetrabutylammonium hydroxide-acetonitrile(75︰25),the detection wavelength was 254 nm and temperture was 40 ℃.The detection limit of cefixime was 2 ng.The method is reliable,specific and accurate,which can be used for quality control of cefixime suspension. |
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| Keywords: | cefixime suspension HPLC related substances |
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