激光诱导间质热疗中的治疗参数选择

目的：考察激光诱导间质热疗中各治疗参数对治疗效果的影响,对各治疗参数进行选择和优化。方法：基于光子传输理论,分别采用Monte Carlo模拟方法和Pennes生物传热方程求解生物组织中的能量分布和温度分布。结果：计算得到了一般加热系统、具有冷却设备的加热系统以及暂时阻断血液灌注条件下,激光波长、功率大小及激光加入头曝光时间对凝结区域大小的影响。结论：激光诱导间质热疗中,需要综合考虑生物组织特性和激光波长、功率及曝光时间等治疗参数来制定治疗方案。

Therapeutic parameter selection during the Laser-induced Interstitial Thermotherapy

Objective:To investigate the influence of different therapeutic parameters on the therapeutic effect, and then to choose and optimize these parameters. Method;Based on the photon transport theory, to solve the energy and temperature distributions using Monte Carlo simulation and Pennes Bio-heat transfer equation,respectively. ResultsiHaving got influences of the laser wavelength, power density and the exposure duration of laser probe on the coagulation size for the ordinary LITTsystem and LITT systems with cooling equipment and blood obstruction,respectively.ConclusiontDuring a LITT treatment, the Rx should be based on the general consideration of different biological properties and the laser wavelength,laser power and the laser probe exposure duration.