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Challenges and solutions for recruiting pregnant smokers into a nicotine replacement therapy trial.
Authors:Kathryn I Pollak  Cheryl A Oncken  Isaac M Lipkus  Bercedis L Peterson  Geeta K Swamy  Pamela K Pletsch  Pauline Lyna  Rebecca J Namenek Brouwer  Laura J Fish  Evan R Myers
Affiliation:Duke Comprehensive Cancer Center, Cancer Prevention, Detection and Control Research Program, Department of Community and Family Medicine, Durham, NC 27705, USA. kathryn.pollak@duke.edu
Abstract:Improvements in smoking cessation interventions for pregnant smokers are needed. One major step is to examine the potential effectiveness of nicotine replacement therapy (NRT). The potential benefits of providing pregnant women with NRT to help them quit smoking are still unknown; early interventions to test the effectiveness and efficacy are vital to advancing the field. This paper describes recruitment efforts for a multiclinic trial to test the effectiveness of NRT use in addition to behavioral therapy in promoting cessation during pregnancy. The biggest challenge is recruiting sufficient numbers of pregnant women. This paper discusses specific obstacles for recruitment and solutions. Knowing the potential pitfalls to recruiting pregnant women into these trials can lead to better studies and thus improved outcomes.
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