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基于DNA链置换的赢家通吃神经网络
引用本文:王宾,李亚,赵宏伟.基于DNA链置换的赢家通吃神经网络[J].电子与信息学报,2021,43(8):2430-2438.
作者姓名:王宾  李亚  赵宏伟
作者单位:大连大学先进设计与智能计算省部共建教育部重点实验室 大连 116622
基金项目:国家重点研发计划重大专项项目(2018YFC0910500),国家自然科学基金(61425002, 61751203, 61772100, 61972266, 61802040, 61672121),辽宁省自认科学基金(20180551241, 2019-ZD-0567)
摘    要:DNA链置换技术广泛用于生物计算中,在计算能力和信息处理方面表现出色。但是,在信号的放大、恢复与比较等一些计算中使用DNA链置换技术,不仅增加DNA链的数量,还会带来额外的计算成本。因此,为了减少DNA链的使用数量,该文构建了一个基于DNA链置换实现的赢家通吃(WTA)神经网络。首先,通过神经元实现逻辑运算AND, NAND和OR,将其级联成WTA神经网络解决了线性不可分问题。通过与别人结果的比较,证明该文采用方法的有效性,并在Visual DSD(DNA链置换)中获得了稳定而直观的结果。然后,为了检验神经元级联的可扩展性,设计了一个3人表决器,并对科学家进行分类,该文展示了分子系统如何表现出与大脑具有类似行为的思考能力,最后证明获得的准确率高于其他方法。

关 键 词:DNA链置换    赢家通吃神经网络    逻辑运算    Visual  DSD
收稿时间:2020-07-15

The Winner-Take-All Neural Network Based on DNA Strand Displacement
Bin WANG,Ya LI,Hongwei ZHAO.The Winner-Take-All Neural Network Based on DNA Strand Displacement[J].Journal of Electronics & Information Technology,2021,43(8):2430-2438.
Authors:Bin WANG  Ya LI  Hongwei ZHAO
Affiliation:Key Laboratory of Advanced Design and Intelligent Computing, Ministry of Education, Dalian University, Dalian 116622, China
Abstract:DNA strand displacement technology is widely used in biological computing, and it has excellent performance in computing power and information processing. However, the use of DNA Strand Displacement (DSD) technology in some calculations, such as signal amplification, restoration, and comparison, not only increases the number of DNA strands, but also brings additional calculation costs. Therefore, in order to reduce the number of DNA strands used, a Winner-Take-All (WTA) neural network based on DNA strand displacement is constructed. Firstly, the logic operations AND, NAND, and OR are realized through neurons, and the linear inseparable problem is solved by cascading them into a WTA neural network. By comparing with the results with others, the effectiveness of the method is proved, and stable and intuitive results are obtained in Visual DSD (DNA Strand Displacement). Then, in order to test the scalability of the neuron cascade, a three-person voter is designed and the scientists are classified. The paper shows how the molecular system demonstrates the ability to think in a similar way to the brain, and finally proves the accuracy is higher than other methods.
Keywords:
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