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A platform for electrochemical sensing of biomolecules based on Europia/reduced graphene oxide nanocomposite
Authors:Hossein Jafari  Mohammad Reza Ganjali  Amin Shiralizadeh Dezfuli  Elmira Kohan
Affiliation:1.Center of Excellence in Electrochemistry, Faculty of Chemistry,University of Tehran,Tehran,Iran;2.Biosensor Research Center, Endocrinology & Metabolism Molecular-Cellular Sciences Institute,Tehran University of Medical Sciences,Tehran,Iran;3.Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine,Iran University of Medical Sciences,Tehran,Iran;4.Department of Chemistry,University of Tabriz,Tabriz,Iran
Abstract:
This study aimed at preparing and evaluating the europium oxide–reduced graphene oxide (rGO) composites. Inorganic nanoparticles anchored onto rGO sheets through a facile sonochemical method. The resultant products were characterized by FT-IR, XRD, SEM. Their activity in biomolecules’ analysis were examined by cyclic voltammetry. The rectified electrodes revealed an incredibly electroactive manner. The obtained progress provided excellent materials for scrutiny of biomolecules. The linear relationship was used in the region of 100–1500 µM ascorbic acid (AA), 50–600 µM dopamine (DA), and 10–700 µM uric acid (UA), between current intensities and concentrations. The detection restrictions (LOD) (S/N?=?3) decreased to 8 µM, 1.1 µM and 0.085 µM for AA, DA and UA respectively by differential pulse voltammetry (DPV).
Keywords:
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