|
|||||
|
|
| PEG相转移催化法合成1-羟甲基苯并三氮唑 | |
| 引用本文： | 邓杨,潘春跃,蔡志红.PEG相转移催化法合成1-羟甲基苯并三氮唑[J].广州化工,2010,38(6):94-96,105. |
| 作者姓名： | 邓杨 潘春跃 蔡志红 |
| 作者单位： | 1. 中南大学化学化工学院,功能有机高分子所,湖南,长沙,410083;广州有色金属研究院焊接材料研究所,广东,广州,510650 2. 中南大学化学化工学院,功能有机高分子所,湖南,长沙,410083 3. 广州有色金属研究院焊接材料研究所,广东,广州,510650 |
| 摘 要： | 研究了在相转移催化剂聚乙二醇(PEG)存在下,苯并三氮唑和甲醛进行亲核加成制备1-羟甲基苯并三氮唑的合成条件。讨论了聚乙二醇分子量、反应物物质的量比、反应温度、反应时间等因素对目标产物收率的影响,得出适合的操作条件为:n(苯并三氮唑):n(甲醛):n(PEG-1000)=1:2:0.01、反应温度25℃、反应时间0.5 h、产品收率达98%。该合成方法具有反应时间短、操作简便、能耗小、溶剂量少等优点。 |
| 关 键 词： | 1-羟甲基苯并三氮唑 相转移催化 聚乙二醇 合成 |
Synthesis of 1 H-Benzotriazole-1-Methanol by Phase-transfer Catalysis |
|
| DENG Yang,PAN Chun-yue,CAI Zhi-hong.Synthesis of 1 H-Benzotriazole-1-Methanol by Phase-transfer Catalysis[J].GuangZhou Chemical Industry and Technology,2010,38(6):94-96,105. | |
| Authors: | DENG Yang PAN Chun-yue CAI Zhi-hong |
| Affiliation: | 1 Institute of Chemistry and Chemical Engineering,Central South University,Hunan Changsha 410083;2 Research Institute of Nonferrous Metals,Guangdong Guangzhou 510650,China) |
| Abstract: | 1H-Benzotriazole-1-Methanol was synthesized by the nucleophlic addition of benzotriazole and formaldehyde using PEG-1000 as a phase transfer catalyst.Various reaction factors influencing the yield of the target product were discussed.The optimum reaction conditions were as follows： the molar ratio of benzotriazole,formaldehyde to PEG-100 was 1：2：0.01,the reaction time was 0.5h,and the reaction temperature was 25℃,with the yield of 98%.So the method had the advantages of short reaction time,simple operation,low energy comsumption,less solvent and so on. |
| Keywords: | 1H-Benzotriazole-1-Methanol phase transfer catalysis polyethylene glycol synthesis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |