Metaphase analysis of metanephric adenoma reveals chromosome Y loss with chromosome 7 and 17 gain |
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| Authors: | JA Brown TJ Sebo JW Segura |
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| Affiliation: | Department of Urology and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA. |
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| Abstract: | A 61-year-old man underwent wedge excision of a 3-cm right renal metanephric adenoma. This recently recognized tumor has been considered benign, although no genetic studies have been reported. Metaphase analysis demonstrated a 47,X,-Y,+7,+17 karyotype. These results are consistent with a clonal neoplastic disorder. |
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