In vivo investigation of the immersion-liquid-induced human skin clearing dynamics

The results of an in vivo investigation of human skin clearing caused by the immersion-liquid-induced matching of the refractive indices are reported for the first time. It was established that subcutaneous injections of a glucose solution produce a significant long-term suppression of the light scattering in the skin dermis, which is an important factor ensuring an increase in efficacy of the optical tomography, photodynamic therapy, and photodestruction of deep objects.