| 哈格曼乙酯与硝基乙烷在不同碱催化下的迈克尔加成反应 |
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| 引用本文： | 胡炳成,吕春绪.哈格曼乙酯与硝基乙烷在不同碱催化下的迈克尔加成反应[J].精细化工,2004,21(11):872-875. |
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| 作者姓名： | 胡炳成 吕春绪 |
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| 作者单位： | 南京理工大学,化工学院,江苏,南京,210094 |
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| 摘 要： | 研究了在不同有机碱催化下,哈格曼乙酯和硝基乙烷经迈克尔加成合成3 甲基 3 (1′ 硝基乙基) 4 乙氧甲酰环己酮的反应。结果表明,氟化四丁基铵的催化效果最好,且当n(氟化四丁基铵)∶n(哈格曼乙酯)=1∶2时,合成产物3 甲基 3 (1′ 硝基乙基) 4 乙氧甲酰环己酮的收率达到最高值56%。
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| 关 键 词： | 哈格曼乙酯 硝基乙烷 3甲基3(1′硝基乙基)4乙氧甲酰环己酮 氟化四丁基铵 迈克尔加成 |
| 文章编号： | 1003-5214(2004)011-0872-04 |
Michael Addition of Hagemann's Ethylester with Nitroethane under the Catalysis of Different Bases |
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| Abstract: | 3- Methyl-3-(1′-nitroethyl)-4-ethoxycarbonylcyclohexanone(Ⅰ) was synthesized through the Michael addition of Hagemann′s ethylester with nitroethane catalyzed by different bases.The results showed that tetrabutylammonium fluoride was the best catalyst for this reaction,and with tetrabutylammonium fluoride and Hagemann′s ethylester in molar ratio 1∶2,the yield of Ⅰ reached the highest value of 56%. |
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| Keywords: | Hagemann′s ethylester nitroethane 3-methyl-3-(1′-nitroethyl)-4-ethoxycarbonylcyclohexanone tetrabutylammonium fluoride Michael addition |
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