Food reinforcement, the dopamine D? receptor genotype, and energy intake in obese and nonobese humans.

[Correction Notice: An erratum for this article was reported in Vol 122(1) of Behavioral Neuroscience (see record 2008-01943-025). In the original article, the n values (and corresponding percentages) for the number of people with the A1/A1 & A1/A2 and A2/A2 genotypes were reversed in Table 2. The corrected table appears in the erratum, with the revised numbers appearing in bold font.] The authors measured food reinforcement, polymorphisms of the dopamine D? receptor (DRD?) and dopamine transporter (DAT1) genes, and laboratory energy intake in 29 obese and 45 nonobese humans 18-40 years old. Food reinforcement was greater in obese than in nonobese individuals, especially in obese individuals with the TaqI A1 allele. Energy intake was greater for individuals high in food reinforcement and greatest in those high in food reinforcement with the TaqI A1 allele. No effect of the DAT1 genotype was observed. These data show that individual differences in food reinforcement may be important for obesity and that the DRD? genotype may interact with food reinforcement to influence energy intake. (PsycINFO Database Record (c) 2010 APA, all rights reserved)