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Computer Simulation for Effect of Tb^3+ on Ca^2+ Speciation in Human Plasma
引用本文:卢兴,王悦,张海元,王进平,牛春吉,倪嘉缵.Computer Simulation for Effect of Tb^3+ on Ca^2+ Speciation in Human Plasma[J].中国稀土学报(英文版),2002,20(3):238-240.
作者姓名:卢兴  王悦  张海元  王进平  牛春吉  倪嘉缵
作者单位:Key Laboratory of Rare Earth Chemistry and Physics,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China
基金项目:ProjectSupportedbytheNationalNaturalScienceFoundationofChina (2 9890 2 80,2 99710 2 9)
摘    要:Becauseoftheexcellentspectroscopicandmagneticpropertiesoftri positivelan thanideionscoupledwiththesimilaritiesbe tweenthemandCa2 + ionparticularlywithre gardtoionicradii,ligandexchangeratesandcoordinationnumbers1] ,manystudieshavefo cusedonapplicationoflan…

关 键 词:稀土  计算机仿真      等离子体

Computer Simulation for Effect of Tb3+ on Ca2+Speciation in Human Plasma
Abstract:Effect of Tb 3+ on Ca 2+ speciation in human plasma was studied by means of the computer program of MINTEQA2. When Tb 3+ ions are not added into the system, Ca 2+ ions mostly distribute in free Ca 2+ (74.7%) and the surplus distributes in Ca 2+ complexes, such as CaHCO 3] +(7.9%), Ca(Lac)] +(6.4%), CaHPO 4 (1 3%), CaHistidinateThreoninateH 3] 3+ (2.4%), CaCitrateHistidinateH 2] (2.3%) and CaCO 3(1.1%). Tb 3+ can compete with Ca 2+ for inorganic as well as biological ligands. An increase of concentration of Tb 3+ in the system results in an increase of content of free Ca 2+ and a decrease of contents of Ca 2+ complexes.
Keywords:rare earths  computer simulation  speciation  human plasma  calcium  terbium
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