| GC/MS/MS法在头发中毒品及代谢物的筛选分析中的应用 |
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| 引用本文： | 沈敏,沈保华,向平.GC/MS/MS法在头发中毒品及代谢物的筛选分析中的应用[J].质谱学报,2002,23(1):11-11. |
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| 作者姓名： | 沈敏 沈保华 向平 |
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| 作者单位： | 司法部司法鉴定科学技术研究所,上海,200063 |
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| 摘 要： | 本文建立了头发中常见滥用药物的GC/MS/MS筛选分析体系。结果表明MS/MS技术通过选择性地采集特定的母离子而避免了基质的干扰.具有质谱SIS的高灵敏度特征和scan提供结构信息的功能。方法回收率为68～101％,最低检出限为0.01～2ng/mg。
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| 关 键 词： | 毒品及代谢物 筛选分析 头发分析 GC/MS/MS |
| 文章编号： | 1004-2997(2002)01-0011-06 |
| 收稿时间： | 2002-03-04 |
The Application of GC/MS/MS to Screening for Drugs of Abused in Hair |
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| SHEN Min,SHEN Bao-hua,XIANG Ping.The Application of GC/MS/MS to Screening for Drugs of Abused in Hair[J].Journal of Chinese Mass Spectrometry Society,2002,23(1):11-11. |
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| Authors: | SHEN Min SHEN Bao-hua XIANG Ping |
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| Abstract: | A screening system was established for simultaneous detection of abused drugs in hair by GC/MS/MS. The results showed that tandem mass spectrometry (MS/MS) technique can effectively reduce the background due to complex matrixes by excluding all unwanted ions except the parent ion, and has advanages of high sensitivity of SIS and structural information of scan. The recoveries of 13 abused drugs range from 68 to 101%, with low limits of detection (0. 01-2ng/mL hair). |
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| Keywords: | abused drugs screening system hair analysis GC/MS/MS |
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