| 乳铁蛋白对肠道屏障保护作用的研究进展 |
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| 引用本文： | 吴洪亚,高亚男,王加启,郑楠.乳铁蛋白对肠道屏障保护作用的研究进展[J].现代食品科技,2023,39(11):371-380. |
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| 作者姓名： | 吴洪亚 高亚男 王加启 郑楠 |
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| 作者单位： | （中国农业科学院北京畜牧兽医研究所，农业农村部奶及奶制品质量安全控制重点实验室，农业农村部奶产品质量安全风险评估实验室（北京），北京 100193） |
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| 基金项目： | 中国农业科学院科技创新工程（ASTIP-IAS12）；财政部和农业农村部：国家现代农业产业技术体系（CARS36） |
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| 摘 要： | 完整的肠道屏障是维持肠道健康的先行和必要条件。乳铁蛋白因其具有多种生物活性而备受推崇。近年来，国内外大量研究报道了乳铁蛋白通过修复肠黏膜、调节免疫功能和肠道菌群等来维持肠道稳态。该研究主要对乳铁蛋白的生物学特性、乳铁蛋白对肠屏障的作用以及乳铁蛋白的应用进行了综述。
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| 关 键 词： | 乳铁蛋白 肠道屏障 保护作用 免疫调节 |
| 收稿时间： | 2022/10/31 0:00:00 |
Advancements on the Protective Effect of Lactoferrin on the Intestinal Barrier |
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| Affiliation: | (Key Laboratory of Quality & Safety Control for Milk and Dairy Products of Ministry of Agriculture and Rural Affairs, Laboratory of Quality and Safety Risk Assessment for Dairy Products of Ministry of Agriculture and Rural Affairs, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China) |
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| Abstract: | An intact intestinal barrier is a prerequisite for maintaining gut health. Lactoferrin is prized for its diverse biological activities. In recent years, numerous studies at home and abroad have reported that lactoferrin promotes intestinal homeostasis by repairing the intestinal mucosa, regulating immune functions, and modulating the intestinal flora. This study primarily reviews the biological characteristics of lactoferrin, its effect on the intestinal barrier, and its applications. |
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| Keywords: | lactoferrin intestinal barrier protective effect immunoregulation |
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