Furan in the baby-food samples purchased from the Finnish markets – Determination with SPME–GC–MS |
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Authors: | Marika Jestoi Talvikki Järvinen Eila Järvenpää Heli Tapanainen Suvi Virtanen Kimmo Peltonen |
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Affiliation: | 1. Finnish Food Safety Authority (Evira), Research Department, Chemistry and Toxicology Unit, Mustialankatu 3, FI-00790 Helsinki, Finland;2. University of Turku, Department of Biochemistry and Food Chemistry, Vatselankatu 2, FI-20014 Turku, Finland;3. National Institute for Health and Welfare, Nutrition Unit, P.O. Box 30, FI-00271 Helsinki, Finland |
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Abstract: | A method applying solid-phase microextraction followed by gas chromatography–mass spectrometric determination was in-house validated and used to study furan concentrations in baby-food samples purchased from the Finnish markets. The validation parameters showed that the method was well applicable for the reliable analysis of furan. Furan was analysed in 21 different baby-food samples as three independent replicates. The mean levels of furan varied between 4.7 and 90.3 μg kg−1 being well in accordance with the levels reported in other studies. The mean concentrations of similar product formulas based on their ingredients were 9.2, 37.0 and 49.6 μg kg−1 for fruit-, vegetables- and meat-containing baby-foods, respectively. According to the statistical analyses, fruit-based baby-food samples had significantly lower concentrations of furan as compared to other formulas. Based on our exercise, it seems that a low margin of safety exists between the extreme worst case infant exposures and the deduced NOAEL of furan on experimental animals, particularly for a clear rodent carcinogen. |
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Keywords: | Furan Baby-food Solid-phase microextraction GC&ndash MS |
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