Microwave-Assisted Synthesis of Glutathione-Capped CdTe/CdSe Near-Infrared Quantum Dots for Cell Imaging |
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| Authors: | Xiaogang Chen Liang Li Yongxian Lai Jianna Yan Yichen Tang Xiuli Wang |
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| Affiliation: | Department of Dermatologic Surgery, Shanghai Skin Disease Hospital, Shanghai 200443, China; E-Mails: (X.C.); (L.L.); (Y.L.); (J.Y.) |
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| Abstract: | These glutathione (GSH)-conjugated CdTe/CdSe core/shell quantum dot (QD) nanoparticles in aqueous solution were synthesized using a microwave-assisted approach. The prepared type II core/shell QD nanoparticles were characterized by UV–Vis absorption, photoluminescence (PL) spectroscopy, X-ray powder diffraction (XRD) and high-resolution transmission electron microscopy (HR-TEM). Results revealed that the QD nanoparticles exhibited good dispersity, a uniform size distribution and tunable fluorescence emission in the near-infrared (NIR) region. In addition, these nanoparticles exhibited good biocompatibility and photoluminescence in cell imaging. In particular, this type of core/shell NIR QDs may have potential applications in molecular imaging. |
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| Keywords: | biomaterials semiconductors near-infrared core/shell quantum dots glutathione molecular imaging |
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