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Controlled chemical modification of the internal surface of photonic crystal fibers for application as biosensitive elements |
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| Affiliation: | 1. Institute of Chemistry, Saratov State University, Astrakhanskaya 83, 410012 Saratov, Russia;2. SPС Nanostructured Glass Technology Ltd, 50 years of October av. 101, 410033, Saratov, Russia;3. Faculty of Nano- and Biomedical Technologies, Astrakhanskaya 83, Saratov State University, 410012 Saratov, Russia;4. Faculty of Physics, Saratov State University, Astrakhanskaya 83, 410012 Saratov, Russia;5. Saint-Petersburg State University, Universitetskii pr. 26, 198504 Saint-Petersburg, Russia;1. College of Applied Science, Harbin University of Science and Technology, Harbin 150080, China;2. Condensed Matter Science and Technology Institute, Harbin Institute of Technology, Harbin 150080, China;3. Materials Research Institute, The Pennsylvania State University, University Park, PA 16802, USA;1. College of Physics, Sichuan University, Chengdu 610064, China;2. College of Information Science and Engineering, Northeastern University, Shenyang 110004, China;3. Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China;1. Grupo de Materia Condensada-UdeA, Instituto de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín, Colombia;2. Centro de Investigación en Ciencias-(IICBA), Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, 62209, Cuernavaca, Morelos, Mexico;3. Universidad EIA, CP 055428, Envigado, Colombia;4. Grupo de Física de Materiales, Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia;5. Cumhuriyet University, Physics Department, 58140, Sivas, Turkey;1. College of Information Science and Engineering, Huaqiao University, Xiamen, Fujian, 361021, China;2. Institute of Optoelectronic Engineering, Jinan University Guangdong, Guangzhou, 510632, China |
| Abstract: | Photonic crystal fibers (PCF) are one of the most promising materials for creation of constructive elements for bio-, drug and contaminant sensing based on unique optical properties of the PCF as effective nanosized optical signal collectors. In order to provide efficient and controllable binding of biomolecules, the internal surface of glass hollow core photonic crystal fibers (HC-PCF) has been chemically modified with silanol groups and functionalized with (3-aminopropyl) triethoxysilane (APTES). The shift of local maxima in the HC-PCF transmission spectrum has been selected as a signal for estimating the amount of silanol groups on the HC-PCF inner surface. The relationship between amount of silanol groups on the HC-PCF inner surface and efficiency of following APTES functionalization has been evaluated. Covalent binding of horseradish peroxidase (chosen as a model protein) on functionalized PCF inner surface has been performed successively, thus verifying the possibility of creating a biosensitive element. |
| Keywords: | Photonic crystal fiber Surface modification Silanization Biosensor PCF"} {"#name":"keyword" "$":{"id":"kwrd0035"} "$$":[{"#name":"text" "_":"photonic crystal fibers HC-PCF"} {"#name":"keyword" "$":{"id":"kwrd0045"} "$$":[{"#name":"text" "_":"hollow core photonic crystal fibers APTES"} {"#name":"keyword" "$":{"id":"kwrd0055"} "$$":[{"#name":"text" "_":"(3-aminopropyl)triethoxysilane GA"} {"#name":"keyword" "$":{"id":"kwrd0065"} "$$":[{"#name":"text" "_":"glutaraldehyde HRP"} {"#name":"keyword" "$":{"id":"kwrd0075"} "$$":[{"#name":"text" "_":"horseradish peroxidase PBS"} {"#name":"keyword" "$":{"id":"kwrd0085"} "$$":[{"#name":"text" "_":"phosphate buffered saline TGA"} {"#name":"keyword" "$":{"id":"kwrd0095"} "$$":[{"#name":"text" "_":"thermogravimetric analysis |
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