2,2-(2,2'-4(S)-苯基-4,5-二氢(噁)唑啉基)丙烷金属络合物对硝酮环加成反应的催化作用

研究了手性双噁唑啉配体2，2-（2，2’-4（S）-苯基-4，5-二氢噁唑啉基）丙烷（5）与铜或锌的配合物对二苯基硝酮（8）与3-（（E）-2-丁烯酰基）-1，3-噁唑烷-2-酮（6）和2，3-二氢呋喃（7）两种烯烃的环加成反应的催化效果。研究结果表明，双噁唑啉金属络合物对硝酮的环加成反应有较好的催化作用，表现在反应速度的提高和立体选择性的改变。比较而言，（5）与铜的配合物具有更好的催化作用。使用二氯亚砜作为氯化试剂对双噁唑啉（5）的合成方法进行了合理的改进，使产率由69．7％提高到89％。

The Catalysis Effect of (4S) - 2,2' - ( 1 - Methylethylidene) bis(4 - phenyl)-4,5 - dihydrooxazole) Metal Complexes on the Cycloaddition Reaction of Nitrone

This paper throws light on the catalysis effect of the complexes of copper(II) or zinc(II) with(4 S)-2,2'-(1-methylethylidene)bis4-(phenyl)-4,5-dihydrooxazole] on the cycloaddition reactions of C,N-diphenylnitrone (8) with 3-((E)-2-Butenoyl)-1,3-oxazolin-2-one(6) or 2,3-dihydrofuran(7).The research results show that chiral bis(oxazoline) metal complexes perform a good effect on the cycloaddition reactions of nitrone,which result in the acceleration of reaction rate and the change of reaction stereo selectivity.The complex of copper(II) with(5) is a better catalyst by contrast with Zinc(II) complex.An effective improvement on the synthesis method of bis(oxazoline)(5) is studied in this article too.The yiled of the product reaches 89% from 69.7% with thionyl chloridizing as chloridizing agent.