The design of a biochip: a self-assembling molecular-scale memory device |
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Authors: | Robinson Bruce H; Seeman Nadrian C |
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Affiliation: | Department of Chemistry, University of Washington Scattle, WA 98195
1Department of Biological Scienes, State University of New York at Albany Albany, NY 12222, USA |
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Abstract: | A design for a biochip memory device based on known materialsand existing principles is presented. The fabrication of thismemory system relies on the self-assembly of the nucleic acidjunction system, which acts as the scaffolding for a molecularwire consisting of polyacetylene-like units. A molecular switchto control current is described which is based on the formationof a charge - transfer complex. A molecular-scale bit is presentedwhich is based on oxidation - reduction potentials of metalatoms or clusters. The readable bit which canbe made of these components has a volume of 3x107 Å3 andshould operate at electronic speeds over short distances. |
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Keywords: | biochip/ nucleic acid junctions/ self-assembly/ molecular electronics/ macromolecular design |
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