| 染料木素的代谢转化及功能活性研究进展 |
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| 引用本文： | 徐梓轩,杨 杨,边 鑫,范 婧,郭晓雪,俞德慧,张 娜.染料木素的代谢转化及功能活性研究进展[J].食品安全质量检测技术,2022,13(5):1359-1366. |
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| 作者姓名： | 徐梓轩 杨 杨 边 鑫 范 婧 郭晓雪 俞德慧 张 娜 |
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| 作者单位： | 哈尔滨商业大学 食品工程学院,哈尔滨商业大学 食品工程学院,哈尔滨商业大学 食品工程学院,哈尔滨商业大学 食品工程学院,哈尔滨商业大学 食品工程学院,哈尔滨商业大学 食品工程学院,哈尔滨商业大学 食品工程学院 |
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| 基金项目： | 国家自然科学基金（32072258）; 中央财政支持地方高校发展专项资金优秀青年人才支持计划项目（2050205）; 哈尔滨商业大学“青年创新人才”支持计划（2019CX06）。 |
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| 摘 要： | 染料木素是一种源自大豆的异黄酮化合物,具有调节胰岛素、抗癌、降血脂等多种生理和药理特性,已经成为预防和治疗多种慢性疾病的潜在药物.近年来,染料木素的生物转化已广泛应用于微生物代谢中,主要涉及我国传统发酵豆制品和肠道菌群微生物代谢,原理是利用菌群和酶促反应将异黄酮转化为具有生物活性的代谢物,将结合型糖苷分解成游离型苷元及...
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| 关 键 词： | 染料木素 微生物代谢 结构 代谢转化 功能活性 |
| 收稿时间： | 2021/12/14 0:00:00 |
| 修稿时间： | 2022/2/19 0:00:00 |
Research progress on metabolic transformation and functional activity of genistein |
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| XU Zi-Xuan,YANG Yang,BIAN Xin,FAN Jing,GUO Xiao-Xue,YU De-Hui,ZHANG Na.Research progress on metabolic transformation and functional activity of genistein[J].Food Safety and Quality Detection Technology,2022,13(5):1359-1366. |
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| Authors: | XU Zi-Xuan YANG Yang BIAN Xin FAN Jing GUO Xiao-Xue YU De-Hui ZHANG Na |
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| Affiliation: | School of food engineering, Harbin Commercial University,School of food engineering, Harbin Commercial University,School of food engineering, Harbin Commercial University,School of food engineering, Harbin Commercial University,School of food engineering, Harbin Commercial University,School of food engineering, Harbin Commercial University,School of food engineering, Harbin Commercial University |
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| Abstract: | Genistein is an isoflavone compound derived from soybeans, it has a variety of physiological and pharmacological properties, such as regulating insulin, anti-tumor, antibacterial, and lowering blood lipids, making it a potential drug for the prevention and treatment of many chronic diseases. In recent years, microbial metabolism has been widely used in the biotransformation of genistein, mainly focusing on the metabolism of traditional fermented soybean products and intestinal flora in my country, it is based on the principle of converting isoflavones into biologically active metabolites by using bacterial colonization and enzymatic reactions to break down bound glycosides into free glycosides and a series of metabolites. This article reviewed the latest research progress of genistein at home and abroad, elaborates its structure, metabolic transformation and functional activity , and prospected the research and application of genistein, we believed that the future research direction needs to further clarify the effects of genistein metabolites on different individual signaling pathways and intestinal flora, which provided scientific guidance for the development of ideal food microbial ferments and the exploitation of flavonoids. |
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| Keywords: | genistein metabolism structure metabolictransformation functionalactivity |
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