| 4-苯基-6-甲基-5-乙酰基-3,4-二氢嘧啶-2-酮的合成 |
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| 引用本文： | 彭秋瑾,牛玉娇,田宇,朱凤祥,李公春.4-苯基-6-甲基-5-乙酰基-3,4-二氢嘧啶-2-酮的合成[J].浙江化工,2010,41(5):8-9. |
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| 作者姓名： | 彭秋瑾 牛玉娇 田宇 朱凤祥 李公春 |
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| 作者单位： | 许昌学院,化学化工学院,河南,许昌,461000 |
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| 摘 要： | 采用氨基磺酸作催化剂,无水乙醇作溶剂,苯甲醛、乙酰丙酮和脲在加热搅拌条件下回流反应3h,合成了4-苯基-6-甲基-5-乙酰基-3,4-二氢嘧啶-2-酮,产率76.0%。
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| 关 键 词： | Biginelli反应 3 4-二氢嘧啶-2-酮 氨基磺酸 |
The Synthesis of 4-Phenyl-6-Methyl-5-Acetyl-3,4-Dihydropyrimidin-2-One |
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| PENG Qiu-jin,NIU Yu-jiao,TIAN Yu,ZHU Feng-xiang,LI Gong-chun.The Synthesis of 4-Phenyl-6-Methyl-5-Acetyl-3,4-Dihydropyrimidin-2-One[J].Zhejiang Chemical Industry,2010,41(5):8-9. |
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| Authors: | PENG Qiu-jin NIU Yu-jiao TIAN Yu ZHU Feng-xiang LI Gong-chun |
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| Affiliation: | PENG Qiu-jin,NIU Yu-jiao,TIAN Yu,ZHU Feng-xiang,LI Gong-chun(College of Chmistry and Chmical Engneering,Xuchang University,Xuchang 461000,China) |
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| Abstract: | 4-Phenyl-6-methyl-5-acetyl-3,4-dihydropyrimidin-2-one was synthesized with catalyst of sulfamic acid,solvent of ethanol,and aromatic aldehydes,acetylacetone and urea by refluxing for 3 h under the conditions of stirring,and the yield can reach 76.0%.The used reaction mechanisms is usually called Biginelli condensation. |
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| Keywords: | Biginelli reaction 3 4-dihydropyrimidin-2-one sulfamic acid |
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