| 聚多巴胺功能化纳米银粒子制备及抗菌性能研究 |
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| 引用本文： | 赵晨旭,左芳,潘丽,王晓丹,廖芝建,秦振立.聚多巴胺功能化纳米银粒子制备及抗菌性能研究[J].精细化工,2014,31(5):545-550. |
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| 作者姓名： | 赵晨旭 左芳 潘丽 王晓丹 廖芝建 秦振立 |
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| 作者单位： | 西南民族大学化学与环境保护工程学院,西南民族大学化学与环境保护工程学院,西南民族大学化学与环境保护工程学院,西南民族大学化学与环境保护工程学院,西南民族大学化学与环境保护工程学院,西南民族大学化学与环境保护工程学院 |
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| 基金项目： | 国家自然科学基金资助项目（No. 50903011, 51273220）；西南民族大学研究生创新型科研项目 (CX2013SZ33) |
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| 摘 要： | 采用一步法,以聚多巴胺(PDA)为还原剂和保护剂,制备PDA功能化的纳米银粒子(PDA-nanoAg)。提出PDA-nanoAg合成机理,并考察其在水相中的分散稳定性。通过紫外-可见吸收分光光度计(UV-Vis)、透射电子显微镜(TEM)、傅里叶变换红外光谱仪(FTIR)对产物形貌和结构进行表征。采用肉汤稀释法测试PDAnanoAg的抗菌性能。结果表明,所制备的PDA-nanoAg平均粒径为50 nm,具有良好的稳定分散性;对埃希氏大肠杆菌(E.coli)、金黄色葡萄球菌(S.aureus)的最小抑菌浓度(MIC)为7.56 mg/L,最小杀菌浓度(MBC)为30.24mg/L。
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| 关 键 词： | 纳米银 聚多巴胺 机理 抗菌性 功能材料 |
| 收稿时间： | 2014/1/21 0:00:00 |
| 修稿时间： | 2014/3/24 0:00:00 |
Study on Preparation and Antibacterial Properties of Polydopamine Functionalized Ag Nanoparticles |
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| ZHAO Chen-xu,ZUO Fang,PAN Li,WANG Xiao-dan,LIAO Zhi-jian and QIN Zhen-li.Study on Preparation and Antibacterial Properties of Polydopamine Functionalized Ag Nanoparticles[J].Fine Chemicals,2014,31(5):545-550. |
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| Authors: | ZHAO Chen-xu ZUO Fang PAN Li WANG Xiao-dan LIAO Zhi-jian and QIN Zhen-li |
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| Affiliation: | Southwest University for Nationalities, College of Chemistry & Environment protection Engineering,Southwest University for Nationalities, College of Chemistry & Environment protection Engineering,Southwest University for Nationalities, College of Chemistry & Environment protection Engineering,Southwest University for Nationalities, College of Chemistry & Environment protection Engineering,Southwest University for Nationalities, College of Chemistry & Environment protection Engineering,Southwest University for Nationalities, College of Chemistry & Environment protection Engineering |
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| Abstract: | Polydopamine (PDA) functionalized silver nanoparticles (PDA-nanoAg) were synthesized by one-step method with PDA as the reductant and protectant. The mechanism for preparation of PDA-nanoAg was proposed. The stable dispersion duration of the as-synthesized Ag nanoparticles in water was also observed. The structure and morphology of PDA-nanoAg particles were investigated by ultraviolet-visible (UV-Vis) absorption spectroscopy, transmission electron microscopy (TEM), and Fourier-transform infrared (FTIR) spectrometry. The antibacterial activity of PDA-nanoAg nanoparticles against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were investigated by broth dilution. The results indicated that the average diameter of the Ag nanoparticles was 50 nm, and PDA-nanoAg particles exhibited good stability in water over a long period of time. The minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) of the as-synthesized Ag nanoparticles against E. coli and S. aureus were 7.56 mg/L and 30.24 mg/L, respectively. |
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| Keywords: | Ag nanoparticles polydopamine mechanism antibacterial property |
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