Bioactive silicon nitride by surface thermal treatment |
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| Affiliation: | 1. Institute of Inorganic Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 845 36 Bratislava, Slovakia;2. Biomedical Research Center of the Slovak Academy of Sciences, Dúbravská cesta 9, 84505 Bratislava, Slovakia;3. Centre for Functional and Surface Functionalized Glass, TnU AD, ?tudentská 2, 911 50 Tren?ín, Slovakia;4. Centre of Excellence for Advanced Materials Application, Slovak Academy of Sciences, Dúbravská cesta 9, 84511, Bratislava, Slovakia;1. Key Laboratory of Advanced Structural Ceramics and Ceramics Matrix Composites, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, China;2. School of Physical Science and Technology, Shanghai Tech University, Shanghai, 201210. China;3. Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China;4. University of Chinese Academy of Sciences, Beijing, 100049, China;1. Ceramic Physics Laboratory, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, 606-8126 Kyoto, Japan;2. Department of Orthopedic Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan;3. Department of Molecular Cell Physiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan;4. The Center for Advanced Medical Engineering and Informatics, Osaka University, Yamadaoka, Suita 565-0871 Osaka, Japan;5. Department of Medical Engineering for Treatment of Bone and Joint Disorders, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0854, Japan;6. Amedica Corporation, 1885 West 2100 South, Salt Lake City, UT 84119, United States;7. Department of Orthopaedic Surgery, University of Missouri, Columbia, MO 65212, United States |
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| Abstract: | Silicon nitride-based ceramics with SiO2, CaO and Ca3(PO4)2 as sintering additives, have been prepared in order to study the bioactivity. Dense ceramic bodies were oxidized by an oxy-acetylene flame at approx. 1475 °C for 60 s, in order to modify the surface in terms of bioactivity enhancement and the formation of optimal porosity for cell viability. During oxidation two concurrent processes occurred on the ceramic body surface: (i) formation of thin glassy layer with a composition close to that of grain boundary phase in ceramic body, and (ii) partial decomposition of silicon nitride matrix. The latter one resulted in the formation of gases (N2 and SiO), which formed bubbles in the viscous surface glassy phase, resulting in porosity required for cell adhesion (small pores) and tissue ingrowth (large pores). The best bioactivity was obtained for oxy-acetylene flame treated Si3N4 ceramics with Ca3(PO4)2 sintering additive. |
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| Keywords: | Silicon nitride Surface modification Flame oxidation Bioactivity |
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