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Facile preparation and characterization of poly(vinyl alcohol)/chitosan/graphene oxide biocomposite nanofibers
Affiliation:1. Department of BIN Fusion Technology, Chonbuk National University, Jeonju 561-756, Republic of Korea;2. Department of Organic Materials and Fiber Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea;3. Department of Chemistry, Inha University, 100 Inharo, Incheon 402-751, Republic of Korea;4. Korea Institute for Knit Industry, 639 Sukam-dong, Iksan-si, Jeollabuk-do 570-330, Republic of Korea;1. Graduate Institute of Applied Science and Technology, 43 Section 4, Keelung Road, Taipei 10607, Taiwan;2. Department of Chemical Engineering, National Taiwan University of Science and Technology, 43 Section 4, Keelung Road, Taipei 10607, Taiwan;3. Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), CIBER en Bioingenieria, Biomateriales y Nanomedicina (CIBER-BBN), C/Jordi Girona 18–26, 08034 Barcelona, Spain;1. Department of Organic and Nano System Engineering, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-701, Republic of Korea;2. Departamento de Quimica, Faculdade de Ciências e Tecnologia da Universidade de Coimbra, 3004-535 Coimbra, Portugal;1. Department of Mechanical Engineering, Ege University, Bornova, Izmir, Turkey;2. Department of Chemistry, Dokuz Eylul University, Buca, Izmir, Turkey;3. İzmir Makine A.Ş., Turgutlu, Manisa, Turkey;4. Department of Mechanical Engineering, Izmir Katip Çelebi University, Çigli, Izmir, Turkey;5. Department of Electrical and Electronics Engineering, Ege University, Bornova, Izmir, Turkey;1. Faculty of Technology and Metallurgy University of Belgrade, Karnegijeva 4, Belgrade 11000, Serbia;2. Vinča Institute of Nuclear Sciences, University of Belgrade, Mike Petrovića Alasa 12–14, Belgrade 11000, Serbia;3. Institute of Oncology and Radiology of Serbia, Pasterova 14, Belgrade 11000, Serbia;4. Department of Mechanical Engineering Kyung Hee University, Yongin 449701, South Korea;5. Department of Chemistry Inha University, Incheon 402751, South Korea;6. Department of Mechanical Engineering University of New Orleans, New Orleans, LA 70148, United States;1. Nanobiophotonics and Laser Microspectroscopy Center, Interdisciplinary Research Institute in Bio-Nano-Sciences and Faculty of Physics, Babes-Bolyai University, M. Kogalniceanu Str 1, 400084 Cluj-Napoca, Romania;2. School of Materials and National Graphene Institute, The University of Manchester, Oxford Road, Manchester M13 9PL, UK;3. Molecular Biology Center, Interdisciplinary Research Institute in Bio-Nano-Sciences and Faculty of Biology, Babes-Bolyai University, M. Kogalniceanu Str 1, 400084 Cluj-Napoca, Romania;4. Hungarian Department of Biology and Ecology, Faculty of Biology and Geology, Babes-Bolyai University, Clinicilor 5-7, 400006 Cluj-Napoca, Romania;5. Nanostructured Materials and Bio-Nano-Interfaces Center, Interdisciplinary Research Institute in Bio-Nano-Sciences and Faculty of Physics, Babes-Bolyai University, M. Kogalniceanu Str 1, 400084 Cluj-Napoca, Romania;6. National Institute for Research and Development of Isotopic and Molecular Technologies, 67-103 Donat Street, 400293 Cluj-Napoca, Romania;7. Physico-Chemical Analysis Center, Interdisciplinary Research Institute in Bio-Nano-Sciences, Babes-Bolyai University, M. Kogalniceanu Str 1, 400084 Cluj-Napoca, Romania;8. Faculty of Chemistry and Chemical Engineering, Babes-Bolyai University,11 Arany Janos, RO-400027 Cluj-Napoca, Romania;9. Institute of Biology, Romanian Academy, Spl. Independentei 296, 060031 Bucharest, Romania;1. Department of Materials Science and Engineering, Sharif University of Technology, Azadi Avenue, P.O. Box 11365-9466, Tehran, Iran;2. School of Science and Technology, Sharif University of Technology, Kish Island Campus, P.O. Box 794177-6655, Iran;3. Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran;4. Institute for Nanoscience and Nanotechnology, Sharif University of Technology, Azadi Avenue, P.O. Box 11365-9466, Tehran, Iran
Abstract:Poly(vinyl alcohol) (PVA)/chitosan (CS)/graphene oxide (GO) biocomposite nanofibers have been successfully prepared using aqueous solution by electrospinning. CS colloidal gel in 1% acetic acid can be changed to homogeneous solution by using electron beam irradiation (EBI). The uniform distributions of GO sheets in the nanofibers were investigated by field emission scanning electron microscopy (FESEM) and Raman spectroscopy. FESEM images illustrated that the spread single GO sheet embedding into nanofibers was formed via self-assembly of GO sheet and PVA/CS chains. And the average diameters of the biocomposite nanofibers decreased (200, 173, 160 and 123 nm) with increasing the contents of GO (0.05, 0.2, 0.4 and 0.6 wt%). Raman spectra verified the presence of GO in the biocomposite nanofibrous mats. The mechanical properties of as-prepared materials related with GO contents. It revealed that the highest tensile strength was 2.78 MPa, which was 25% higher than that of neat PVA/CS nanofibers. Antibacterial test demonstrated that the addition of GO to PVA/CS nanofiber had great ability to increase inhibition zone till 8.6 mm. Overall, these features of PVA/CS/GO nanofibers which were prepared by eco-friendly solvent can be a promising candidate material in tissue engineering, wound healing and drug delivery system.
Keywords:Electrospinning  Poly(vinyl alcohol)  Chitosan  Graphene oxide  Nanofibers  Biomaterials
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